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. 2024 Jun 6;28(11):e18450. doi: 10.1111/jcmm.18450

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© 2024 The Author(s). Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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DCTN2 knockdown inhibits HCC cell proliferation and metastasis. (A, B) qPCR and western blot showing the expression of DCTN2 in several HCC cell lines. (C–F) qPCR and western blot confirmed the konckdown efficiency of DCTN2 in HepG2 and MHCC97H cell lines. (G, H) CCK‐8 assay demonstrated that DCTN2 silence repressed HCC cell proliferation. (I–L) Transwell invasion and wound healing assays showed DCTN2 knockdown inhibited the metastasis capacity of HCC cells. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.