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. Author manuscript; available in PMC: 2024 Jun 6.
Published in final edited form as: Resuscitation. 2023 Feb 16;186:109735. doi: 10.1016/j.resuscitation.2023.109735

Figure 4: Circulating Cardiac Troponin I Concentrations in Swine Resuscitated with T3np, T3np+PCR, and EPI Before and After Cardiac Arrest.

Figure 4:

Circulating cTnI concentrations were low, but detectable, at baseline and did not exceed the 99th percentile of normal animals (0.04 ng/mL). Within the first hour after ROSC, circulating cTnI levels rose in all animals, but the magnitude of cTnI elevation was greater in EPI-treated animals compared with animals treated with either T3np formulation. Values are mean±SEM. *p<0.05 vs. EPI; †p=0.06 vs. EPI. cTnI = cardiac troponin I; ROSC = return of spontaneous circulation; T3np = triiodothyronine nanoparticles; T3np+PCr = triiodothyronine nanoparticles with encapsulated phosphocreatine