Table 1. Outcomes of the Colocalization Analysis after MR Study with cis-pQTLsa.
| MR results |
||||||||
|---|---|---|---|---|---|---|---|---|
| PMID | Uniprot | protein names | outcomes | method | nSNP | OR(95% CI) | P value | PP.H4.abf |
| 34857953 | O95236 | APOL3 | sepsis (28 day mortality) | WR | 1 | 0.87(0.80–0.95) | 0.002046461 | 0.518702543 |
| 34857953 | P22392 | NDKB& | sepsis (28 day mortality) | WR | 1 | 0.41(0.26–0.65) | 0.000162427 | 0.922110503 |
| 35078996 | P08174 | complement decay-accelerating factor (CD55)# | sepsis (28 day mortality) | WR | 1 | 1.42(1.13–1.77) | 0.002465158 | 0.529747802 |
| 29875488 | P08174 | complement decay-accelerating factor (CD55)# | sepsis (28 day mortality) | WR | 1 | 1.25(1.08–1.46) | 0.003156166 | 0.507980692 |
| 28240269 | P08174 | complement decay-accelerating factor (CD55)# | sepsis (28 day mortality) | WR | 1 | 1.26(1.10–1.44) | 0.001082243 | 0.726193226 |
| 34857953 | Q86VZ4 | LRP11 | sepsis (death vs survived) | WR | 1 | 0.73(0.60–0.89) | 0.002113459 | 0.518673042 |
| 34857953 | P22392 | NDKB& | sepsis (death vs survived) | WR | 1 | 0.42(0.25–0.69) | 0.000781606 | 0.743190218 |
| 35078996 | P00491 | PNP | sepsis (death vs survived) | IVW | 2 | 1.52(1.19–1.95) | 0.000817079 | 0.824065552 |
| 35078996 | Q9BPX1 | 17-beta-hydroxysteroid dehydrogenase 14 (HSD17B14) | sepsis (death vs survived) | WR | 1 | 0.50(0.32–0.78) | 0.002569258 | 0.561121153 |
| 35078996 | Q06481 | APLP2 | sepsis (death vs survived) | WR | 1 | 1.48(1.13–1.93) | 0.00424199 | 0.512768759 |
| 28240269 | P98066 | TNFAIP6 | sepsis (death vs survived) | WR | 1 | 1.34(1.10–1.62) | 0.003008802 | 0.552163903 |
| 28240269 | P08174 | complement decay-accelerating factor (CD55)# | sepsis (death vs survived) | WR | 1 | 1.30(1.11–1.51) | 0.001140351 | 0.735431777 |
a
The symbols “#” and “&” indicate that the protein is concurrently present in two distinct outcome databases.