Table 1.
Demographic and clinicopathological characteristics of patients with nonsmall cell lung cancer
| Characteristics | Total [n (%)] | Training cohort [n (%)] |
Validation cohort [n (%)] |
P value |
|---|---|---|---|---|
| Age | 0.949 | |||
| <60 | 10909 (26.7) | 7799 (26.7) | 3110 (26.6) | |
| 60–70 | 14758 (36.1) | 10549 (36.2) | 4209 (36.1) | |
| >70 | 15186 (37.1) | 10833 (37.1) | 4353 (37.3) | |
| Sex | 0.842 | |||
| Female | 21170 (51.8) | 15112 (51.8) | 6058 (51.9) | |
| Male | 19683 (48.2) | 14069 (48.2) | 5614 (48.1) | |
| Race | 0.405 | |||
| White | 33903 (82.98) | 24255 (83.1) | 9648 (82.7) | |
| Black | 3729 (9.12) | 2629 (9) | 1100 (9.4) | |
| Others | 3221 (7.88) | 2297 (7.9) | 924 (7.9) | |
| Assistant treatment | 0.985 | |||
| Neither | 22767 (55.729) | 20070 (68.8) | 8018 (68.7) | |
| Radiotherapy | 1081 (2.64) | 711 (2.4) | 279 (2.4) | |
| Chemotherapy | 2225 (5.44) | 5499 (18.8) | 2214 (19) | |
| Both | 1045 (2.55) | 2901 (9.9) | 1161 (9.9) | |
| Histological type | 0.254 | |||
| Adenocarcinoma | 22767 (55.729%) | 16283 (55.8) | 6484 (55.6) | |
| Adenosquamous carcinoma | 1081 (2.64%) | 736 (2.5) | 345 (3) | |
| Bronchi alveolar carcinoma | 2225 (5.44%) | 1578 (5.4) | 647 (5.5) | |
| Large cell carcinoma | 1045 (2.55%) | 753 (2.6) | 292 (2.5) | |
| NSCLC (unspecified) | 1134 (2.77%) | 815 (2.8) | 319 (2.7) | |
| Squamous cell carcinoma | 10632 (26.02%) | 7588 (26) | 3044 (26.1) | |
| Other | 1969 (4.81%) | 1428 (4.9) | 541 (4.6) | |
| MLNR | ||||
| Median (range) | 0 (0-1) | 0 (0-1) | 0 (0-1) | 0.586 |
| ELNs | ||||
| Median (range) | 8 (0-90) | 8 (0-90) | 8 (0-90) | 0.432 |
| AJCC 8th T stage | 0.957 | |||
| T1a | 1687 (4.13) | 1199 (4.1) | 488 (4.2) | |
| T1b | 8744 (21.41) | 6255 (21.4) | 2489 (21.3) | |
| T1c | 6824 (16.70) | 4862 (16.7) | 1962 (16.8) | |
| T2a | 10567 (25.86) | 7583 (26) | 2984 (25.6) | |
| T2b | 3086 (7.53) | 2185 (7.5) | 901 (7.7) | |
| T3 | 5837 (14.28) | 4159 (14.3) | 1678 (14.4) | |
| T4 | 4108 (10.06) | 2938 (10.1) | 1170 (10) |
ELNs, examined lymph node numbers; MLNR: metastatic lymph node ratio; NSCLC, nonsmall cell lung carcinoma; NSCLC (unspecified), non-small cell lung carcinoma (unspecified but not listed above); Other, other malignant tumors categories other than above and small cell lung cancer in SEER database.