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. Author manuscript; available in PMC: 2024 Jun 6.
Published in final edited form as: J Am Chem Soc. 2023 Dec 22;146(1):677–694. doi: 10.1021/jacs.3c10406

Table 8.

Conformation exchange parameters for exchange between the A- and Z-form of the 8mG4 r(CpG)3 construct measured from ZZ-exchange.

Residue pA (%) at 25°C (from ratio of peak intensities) pA (%) at 25°C (from ratio of Kex) kAZ (s−1) at 25°C kZA (s−1) at 25°C
Gua2 C8 42.0 48.6 5.4 ± 1.1 5.1 ± 0.7
Cyt3 C6 40.2 48.4 4.6 ± 0.7 4.3 ± 1.0
Gua6 C8 55.1 53.7 4.8 ± 0.5 5.6 ± 0.4