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. 2024 Jun 6;19(6):e0305047. doi: 10.1371/journal.pone.0305047

Table 2. TOP 4 ATC groups 1st level and the associated 3rd level subgroups with the two most frequently prescribed drugs.

Drug groups (ATC Classification System) n patients (%) Most frequent drugs (n patients)
AAlimentary tract and metabolism
A02B Drugs for peptic ulcer and GORD1
A04A Antiemetics and antinauseants
A06A Drugs for constipation

71 (88.8)
45 (56.3)
42 (52.5)

Pantoprazole (66), Esomeprazole (22)
Ondansetron (38), Dimenhydrinate (23)
Macrogol, combinations (28), Sodium picosulfate (13)
NNervous system
N02B Other analgesics and antipyretics
N02A Opioids
N05C Hypnotics and sedatives

72 (90.0)
65 (81.3)
38 (47.5)

Metamizole sodium (68), Paracetamol (40)
Piritramide (42), Oxycodone (40)
Zopiclone (27), Melatonin (10)
BBlood and blood-forming organs
B05B i.v. solutions2
B01A Antithrombotic agents
B05X i.v. solution additives2

60 (75.0)
76 (95.0)
38 (47.5)

Electrolytes (59), Combinations (24)
Enoxaparin (75), Acetylsalicylic acid (12)
Combination of electrolytes and trace elements (26), Potassium chloride (24)
J–Antiinfectives for systemic use
J01D Other beta-lactam antibacterials
J01X Other antibacterials
J01C Beta-lactam antibacterials, penicillins

52 (65.0)
43 (53.8)
26 (32.5)

Ceftriaxone (26), Meropenem (22)
Metronidazole (44), Vancomycin (14)
Piperacillin and BLI3 (15), Ampicillin and BLI3 (11)

1 Gastro-Oesophageal Reflux Disease

2 B05B: i.v. solutions include solutions for parenteral nutrition or for the electrolyte balance.

B05X: Additives are concentrated solutions containing electrolytes, vitamins or amino acids for correcting electrolyte balance

and nutritional status.

3 BLI = Beta-lactamase inhibitor