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. 2024 Jun 6;19(6):e0305047. doi: 10.1371/journal.pone.0305047

Table 3. Top 5 reasons for PIs sorted by main categories according to DokuPIK.

Reasons for PIs by main categories and subcategories n (%) Acceptancea [%]
Category Drug
    (Clear) indication, but no drug prescribed
    Inappropriate (or not most suitable) drug formulation in terms of indication
    (Clear) indication not (or no longer) given
175 (60.8)
76 (26.4)
43 (14.9)
31 (10.8)
91.4
97.3
90.7
80.6
Category Other
    Patient counselling or education
58 (20.1)
30 (10.4)
100.0
100.0
Category Dose
    (Inappropriate) dose
49 (17.0)
18 (6.3)
97.9
94.4
Top five subcategories 198 (68.8) 92.8
Total 288 (100.0) 94.0

aAcceptance rate of PIs refers to n = 266, excluding PIs where only information was provided to physicians, nurses or patients.