Fig. 2.

Human iPSC-derived airway organoids (iPSC-AO) are vulnerable to SARS-CoV-2 infection. (A) Schematic illustration of SARS-CoV-2 virus infection in AO. (B) Time-lapse images of SARS-CoV-2-infected AO. The white arrow indicated the same organoid in the mock group, and black arrow indicated the same organoids in the infection group. (C) Immunofluorescence staining of N protein and S protein in SARS-CoV-2-infected AO. Nuclei were counterstained with DAPI (blue). Scale bar = 20 µm. (D) Transmission electron microscope analysis detected successful SARS-CoV-2 virus infection in AO, indicated by arrow. Scale bar = 200 nm. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)