Table 3.
Univariate and multivariate Cox risk regression model on overall survivals of body composition score in study participants.
| Variables | OS (Model 1) | OS (Model 2) | OS (Model 3) | OS (Model 4) | ||||
|---|---|---|---|---|---|---|---|---|
| Crude HR (95% CI) | Crude P | Adjusted HR (95% CI) | Adjusted P | Adjusted HR (95% CI) | Adjusted P | Adjusted HR (95% CI) | Adjusted P | |
| Overall | 2.101 (1.721–2.565) | < 0.001 | 2.507 (2.000–3.142) | < 0.001 | 2.037 (1.647–2.519) | < 0.001 | 2.036 (1.644–2.521) | < 0.001 |
| Sub-group by tumor type | ||||||||
| Gastric cancer | 1.474 (0.915–2.375) | 0.111 | 1.456 (0.828–2.559) | 0.192 | 1.471 (0.788–2.747) | 0.225 | 2.035 (0.783–5.290) | 0.145 |
| Colorectal cancer | 2.339 (1.637–3.343) | < 0.001 | 2.900 (1.903–4.419) | < 0.001 | 2.699 (1.758–4.142) | < 0.001 | 2.693 (1.755–4.132) | < 0.001 |
| Hepatocellular carcinoma | 2.960 (1.553–5.643) | 0.001 | 4.775 (2.242–10.172) | < 0.001 | 4.944 (2.485–9.836) | < 0.001 | 4.863 (2.451–9.649) | < 0.001 |
| Esophageal cancer | 2.061 (1.050–4.047) | 0.036 | 2.360 (1.151–4.841) | 0.019 | 2.980 (1.263–7.026) | 0.013 | 4.431 (1.472–13.335) | 0.008 |
| Pancreatic cancer | 2.040 (1.192–3.492) | 0.009 | 2.807 (1.581–4.983) | < 0.001 | 2.807 (1.581–4.983) | < 0.001 | 1.905 (1.127–3.219) | 0.016 |
| Biliary system malignancies | 1.577 (0.590–4.213) | 0.363 | 4.073 (1.075–15.430) | 0.039 | 5.016 (1.262–19.936) | 0.022 | 23.829 (1.242–457.310) | 0.035 |
Model 1: unadjusted; Model 2: adjusted for age, sex, stage, tumor type; Model 3: adjusted for age, sex, stage, tumor type, KPS score, PG-SGA, HRQoL; Model 4: adjusted for age, sex, stage, tumor type, KPS score, PG-SGA, HRQoL, Alb, PLR, OPNI, BMI, MAC, MAMC, HGS, ECW/TBW.
KPS, Karnofsky Performance Status; PG-SGA, the Patient-Generated Subjective Global Assessment; HRQoL, health-related quality of life; BMI, body mass index; Alb, albumin; PLR, platelet to lymphocyte ratio; OPNI, Onodera’s prognostic nutritional index; MAC, circumference of the mid-upper arm; MAMC, mid-upper arm muscle circumference; HGS, grip strength of the non-dominant hand; ECW, extracellular water; TBW, total body water.