Table 6.
Multivariate Cox analysis of overall survival and progression-free survival.
| Factor | Overall Survival | Progression Free Survival | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P - value | HR | 95%CI | P - value | |
| Perineural invasion | ||||||
| Without vs. With | 2.568 | 1.013∼6.512 | 0.047 | |||
| Pathological stage | ||||||
| Stage I | 1.000 | 1.000 | ||||
| Stage II | 46.731 | 6.832∼319.651 | <0.001 | 29.655 | 6.914∼127.191 | <0.001 |
| Stage III | 16.964 | 4.276∼67.295 | <0.001 | 7.971 | 2.913∼21.813 | <0.001 |
| FFA/Alb | ||||||
| <9.812 vs. ≥9.812 | 0.576 | 0.344∼0.962 | 0.035 | 0.655 | 0.430∼0.998 | 0.049 |
| Smoking status | ||||||
| Never vs. Current/past | 2.052 | 1.121∼3.754 | 0.020 | |||
| Adjuvant radiation therapy | ||||||
| No vs. Yes | 3.501 | 2.136∼5.739 | <0.001 | |||
| LNs | ||||||
| <10 | 1.000 | |||||
| 10∼19 | 0.481 | 0.255∼0.909 | 0.024 | |||
| ≥20 | 0.646 | 0.402∼1.037 | 0.070 | |||
| T stage | ||||||
| T1 | 1.000 | |||||
| T2 | 2.551 | 0.968∼6.719 | 0.058 | |||
| T3 | 2.508 | 1.093∼5.752 | 0.030 | |||
| T4 | 1.939 | 1.139∼3.303 | 0.015 | |||
| N stage | ||||||
| N0 | 1.000 | |||||
| N1 | 3.760 | 0.656∼21.561 | 0.137 | |||
| N2 | 3.013 | 0.879∼10.332 | 0.079 | |||
| N3 | 2.558 | 1.128∼5.803 | 0.025 | |||
| Tumor location | ||||||
| Superior lobe of left lung | 1.000 | |||||
| Inferior lobe of left lung | 0.530 | 0.288∼0.975 | 0.041 | |||
| Superior lobe of right lung | 0.847 | 0.450∼1.596 | 0.607 | |||
| Middle lobe of right lung | 0.613 | 0.335∼1.120 | 0.112 | |||
| Inferior lobe of right lung | 0.757 | 0.375∼1.527 | 0.437 | |||
FFA/Alb, serum free fatty acid/albumin ratio; LNs, Number of lymph nodes removed surgically.