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. 2024 May 24;15:1405423. doi: 10.3389/fphar.2024.1405423

TABLE 5.

Marketed Drug Products for AD recently approved by FDA.

Drug name (active) Therapy Company Trial commencement Type of clinical trial conducted for AD (trial ID) Dosage form References
Rexulti (Brexpiprazole) Immunotherapy against Aβ aggregates Otsuka 10 May 2023 Phase 3, multicenter,12-week, randomized, double-blind, placebo-controlled trial (NCT03548584) Tablet for oral dose Lee et al. (2023)
Leqembi (lecanemab-irmb) Immunotherapy against Aβ aggregates Biogen 6 July 2023 Phase 3, 18-month, multicenter, double-blind, trial (NCT03887455) Injection for Intravenous Infusion Practical Neurology (2023)
Aduhelm (Aducanumab) Immunotherapy against Aβ aggregates Biogen 7 June 2021 Two Phase 3, randomized, double-blind, placebo controlled (NCT02484547 and NCT02477800) Injection for Intravenous Infusion Budd Haeberlein et al. (2022)