TABLE 5.
Marketed Drug Products for AD recently approved by FDA.
| Drug name (active) | Therapy | Company | Trial commencement | Type of clinical trial conducted for AD (trial ID) | Dosage form | References |
|---|---|---|---|---|---|---|
| Rexulti (Brexpiprazole) | Immunotherapy against Aβ aggregates | Otsuka | 10 May 2023 | Phase 3, multicenter,12-week, randomized, double-blind, placebo-controlled trial (NCT03548584) | Tablet for oral dose | Lee et al. (2023) |
| Leqembi (lecanemab-irmb) | Immunotherapy against Aβ aggregates | Biogen | 6 July 2023 | Phase 3, 18-month, multicenter, double-blind, trial (NCT03887455) | Injection for Intravenous Infusion | Practical Neurology (2023) |
| Aduhelm (Aducanumab) | Immunotherapy against Aβ aggregates | Biogen | 7 June 2021 | Two Phase 3, randomized, double-blind, placebo controlled (NCT02484547 and NCT02477800) | Injection for Intravenous Infusion | Budd Haeberlein et al. (2022) |