Table 3.

Summary of five fetal anemia case reports and their therapeutic interventions due to anti-M alloimmunization.

No	author	year	country	Interventions	average gestational age at diagnosis	average GA at first intervention	Delivery	outcomes
1	Furukawa et al. [12]	1993	Japan	plasmapheresis 6 times on a biweekly program	–	12 weeks of gestation	–	Intrauterine death
2	Furukawa et al. [12]	1993	Japan	plasmapheresis therapy, 56 Liter	–	2 months of gestation	Normal delivery with induction, 35 weeks	Alive, initiated phototherapy, normal developing
3	Seo et al. [13]	2007	South Korea	Fetal intravascular transfusions, 2 times	32 weeks+2 days	32 weeks+2 days	Normal delivery with induction, 35 weeks	Alive, initiated phototherapy, and one time transfusion for newborn
4	Bajpayee et al. [14]	2014	India	Intrauterine transfusion, 3 times	20 weeks	28 weeks	C-section	Alive, mild jaundice at birth receiving phototherapy for newborn, normal developmental and hematological follow-up after 12 months
5	Li et al. [9]	2017	China	Intrauterine transfusions, 5 times	22 weeks+5 days	22 weeks+6 days	elective cesarean section, 36 weeks	Alive, two blood transfusion for the neonate after birth, normal developmental follow-up until 6 months
6	Hubinont et al. [16]	2017	Belgium	plasma exchange twice a week and daily low molecular weight heparin injection, 1 Intrauterine transfusions	–	–	–	Intrauterine death at 20 weeks
7	Hubinont et al. [16]	2017	Belgium	Plasmapheresis at 7 weeks and twice a week and changed to 3/week after 12 weeks,	–	7 weeks+5 days	Cesarean, 32 weeks+6 days	Alive, Phototherapy was initiated, discharged after 3 weeks
8	Maki et al. [15]	2020	Japan	Intraperitoneal transfusion due to unsuitable position of umbilical cord for intrauterine transfusion	19 weeks	24 weeks	–	Fetal death
9	Maki et al. [15]	2020	Japan	Plasma Exchange, 25 times; intrauterine transfusion, 1 time	13 weeks	14 weeks	Normal delivery, 31 weeks	Alive, 11 days phototherapy and five transfusion for neonate, discharge at day 46 without abnormal neurological findings