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. 2024 Jun 6;17:41. doi: 10.1186/s13045-024-01564-3

Table 3.

Examples of ferroptosis inhibitors

Class Name References
ACSL4 inhibitor Triacsin C, troglitazone, rosiglitazone [374376]
ALOX inhibitor Zileuton, MK886, PD146176, baicalein, LOXBlock-1 [33, 42, 45, 377, 378]
DPP4 inhibitor Vildagliptin, alogliptin, linagliptin [30, 360]
Iron chelator Deferoxamine (DFO), 2,2-bipyridyl, ciclopirox olamine (CPX), deferiprone, pioglitazone [9, 324, 379, 380]
Lipid peroxidation inhibitor Ferrostatins (e.g., ferrostatin-1, SRS11-92, SRS12-45, SRS13-35, SRS13-37, and SRS16-86), liproxstatin-1 [9, 45]
Lysosome and autophagy inhibitor Ammonium chloride, bafilomycin A1, chloroquine, wortmannin, 3-methyladenine, cryptotanshinone, CA-074Me, pepstatin A, E64 [381385]
Mitochondrial ROS inhibitor XJB-5–131, JP4-039, mitoTEMPO, MitoQ [226, 386, 387]
NOX inhibitor 2-acetylphenothiazine, diphenyleneiodonium chloride (DPI) [9, 30]
Broad-spectrum antioxidant Vitamin E, vitamin K, n-acetylcysteine (NAC), butylated hydroxyltoluene (BHT), GSH and CoQ10 [9, 108, 388390]
FDFT1 inhibitor Zaragozic acid A, YM-53,601 [40]
STING1 inhibitor H-151 [355]
CTSB inhibitor CA-074Me [181]