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. 2007 Sep 28;98(12):1959–1964. doi: 10.1111/j.1349-7006.2007.00628.x

Figure 1.

Figure 1

Subcellular localization of hematoporphyrin monomethyl ether (HMME) in NuTu‐19 cells derived from adenocarcinoma of Fischer 344 rat. Fluorescence images of the cells double‐stained with HMME and mitochondria fluorescent probe (Rhodamine‐123; Sigma) or cytolysosome fluorescent probe (Lucifer Yellow; Sigma) are shown. Cells were observed at various time intervals (0.5, 1, 2, 3, 6, and 12 h) following coincubation of HMME and Rhodamine‐123 or Lucifer Yellow. (a) HMME + Rhodamine‐123; (b) HMME + Lucifer Yellow; (c) HMME alone; (d) Rhodamine‐123 alone; (e) Lucifer Yellow alone. All photos were taken 3 h after incubation.