. 2008 Oct 3;99(10):1924–1932. doi: 10.1111/j.1349-7006.2008.00947.x

Table 3.

Correlation between methylation status of γ‐synuclein and clinicopathological factors of colorectal cancer patients

Variable	n	Unmethylation Index percentage		P‐value	Methylation status (n)			P‐value
Variable	n	Mean ( ± s) ^¶	Median (range)	P‐value	u ^¶	m + u ^¶	m ^¶	P‐value
Age
≥ 60	34	52.84 ± 34.50	56.69 (84.32)	0.340 ^†	13	11	10	0.393 ^§
< 60	33	59.34 ± 34.47	82.31 (87.01)		17	10	6
Sex
Male	37	54.50 ± 36.19	68.38 (86.93)	0.612 ^†	16	11	10	0.401 ^§
Female	30	57.93 ± 32.51	68.48 (83.45)		14	10	6
Histological types
Differentiated	62	54.65 ± 34.58	61.73 (87.01)	0.298 ^†	27	19	16	0.301 ^§
Undifferentiated	5	73.24 ± 29.49	86.84 (70.11)		3	2	0
Stage
I	17	35.27 ± 32.86	15.01 (82.52)	< 0.0001 ^‡	3	5	9	0.003 ^§
II	19	52.40 ± 31.96	42.55 (83.65)		7	10	2
III	26	66.25 ± 32.95	85.90 (85.31)		15	6	5
IV	5	89.35 ± 2.410	88.69 (5.900)		5	0	0
Lymph node invasion
Positive	30	68.88 ± 31.32	87.25 (84.84)	0.009 ^†	19	6	5	0.025 ^§
Negative	37	45.62 ± 33.58	28.98 (85.33)		11	15	11
Distant metastasis
Positive	5	89.35 ± 2.410	88.69 (5.900)	0.039 ^†	5	0	0	0.049 ^§
Negative	62	53.35 ± 34.35	56.69 (87.01)		25	21	16

^{^†}

Calculated by the Mann–Whitney U‐test.

^{^‡}

^‡ Calculated by Spearman's correlation analysis.

^{^§}

^§ Calculated by Fisher's exact test.

^{^¶}

Inline graphic ± s: mean ± standard deviation. m: completely methylated; m + u: partially unmethylated or partially methylated; u, completely unmethylated.