Table 2.
IC50 values for MIAPaCa‐2 and its dFdCyd‐resistant cells, MIAPaCa‐2/dFdCyd
| Cell Line | Compound | IC50 value (µM) | Resistant ratio |
|---|---|---|---|
| MIAPaCa‐2 | dFdCyd | 0.00692 ± 0.00228 | – |
| TAS‐106 | 0.00625 ± 0.00110 | – | |
| MIAPaCa‐2/dFdCyd | dFdCyd | 17.58667 ± 1.63016 | 2541 |
| TAS‐106 | 0.00627 ± 0.00073 | 1.00 |
Growth inhibition was determined as described in Materials and Methods section. IC50 values are given as mean values (in µM) ± standard error of the mean (SEM) of three independent experiments. Resistant ratio was the ratio of IC50 values for resistant variants to that for the respective parental cell lines.