Figure 4.
Antitumor activity of cepharanthin (CEP) in CCA‐inoculated NOD/Scid/Jak3 KO mice. Mice were inoculated with 4 × 106 cells of KKU‐M213 and KKU‐M214 in each flank and intraperitoneally injected with PBS or CEP every day for 17 days thereafter. (a) Average body weights of the mice in each group were compared. (b) CCA tumor tissues were obtained from placebo and CEP‐treated mice. (c) Comparison of tumor weights were obtained from placebo and CEP‐treated mice. **P < 0.05; *P < 0.001 independent‐sample t‐test compared to the placebo group.