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. 2008 May 19;99(7):1304–1310. doi: 10.1111/j.1349-7006.2008.00839.x

Figure 3.

Figure 3

Lack of core fucosylation of EGFR leads to the suppression of EGF signaling and cell growth. EGF binding to the high‐affinity type of EGFR is significantly reduced in Fut8−/– cells, and that leads to dysfunction of EGF signaling and cell growth.