Table 2.

Clinicopathologic characteristics and LOH statuses in 80 patients

Patient number	AJCC pT classification	Results of LOH analysis of chromosomal arm					Tumor diameter (maximum; cm)	Tumor number (nodules)	Grade (1–3)	AFP (ng/mL)	vp †	Recurrence free survival (months)	Recurrence	Sites of the recurrence
		1p	3p	9p	10q	17p
1	1	R	LOH	NI	R	LOH	3.5	1	1	4	0	91	No
2	1	R	NI	R	R	R	0.9	1	1	5	0	87	No
3	1	LOH	R	LOH	LOH	LOH	2.3	1	2	4	0	78	No
4	1	LOH	R	NI	LOH	LOH	0.9	1	2	3	0	77	No
5	1	LOH	LOH	NI	R	R	0.9	1	1	60	0	77	No
6	1	R	R	LOH	R	R	2.0	1	1	3	0	48	No
7	1	LOH	NI	R	R	LOH	2.1	1	2	29	0	65	No
8	1	R	LOH	NI	NI	LOH	2.7	1	1	32	0	109	No
9	1	NI	LOH	NI	LOH	LOH	3.2	1	1	21	0	59	No
10	1	LOH	R	R	R	R	1.2	1	2	10	0	92	No
11	1	LOH	R	R	R	R	1.0	1	2	102	0	73	No
12	1	R	R	LOH	R	LOH	1.8	1	2	6	0	22	No
13	1	R	LOH	R	R	R	2.0	1	1	38	0	88	No
14	1	LOH	R	LOH	R	R	1.0	1	2	29	0	71	No
15	1	NI	R	NI	R	R	1.5	1	2	32	0	11	No
16	1	R	LOH	NI	R	R	1.1	1	2	3	0	59	No
17	1	R	R	R	R	R	2.0	2	1	11	0	40	No
18	2	LOH	R	LOH	R	NI	1.5	2	2	8	0	89	No
19	2	R	R	R	LOH	LOH	4.2	2	2	51	0	86	No
20	2	LOH	LOH	R	R	LOH	1.5	3	1	11	0	86	No
21	2	R	R	LOH	LOH	NI	6.0	1	3	3317	1	85	No
22	2	LOH	NI	R	LOH	LOH	1.8	2	2	36	0	84	No
23	2	LOH	R	R	R	LOH	3.3	5	2	16	0	82	No
24	2	NI	LOH	LOH	R	LOH	4.2	10	2	1	1	81	No
25	2	R	R	LOH	LOH	LOH	2.7	3	2	29	0	77	No
26	2	LOH	R	R	R	R	2.1	1	1	434	1	75	No
27	2	LOH	R	LOH	LOH	LOH	2.4	3	2	6	1	73	No
28	2	LOH	R	R	R	LOH	3.1	5	3	37	1	72	No
29	2	R	R	R	R	R	2.7	5	3	9	1	70	No
30	2	LOH	R	R	R	NI	3.6	6	1	1490	1	55	No
31	2	LOH	LOH	NI	R	R	3.0	2	3	3	0	72	No
32	2	LOH	R	LOH	R	LOH	1.4	3	1	42	0	63	No
33	2	LOH	R	R	R	R	2.8	6	2	12	0	51	No
34	2	R	R	NI	R	LOH	2.5	16	2	34	1	39	No
35	2	R	R	LOH	LOH	LOH	1.9	137	2	1276	1	49	No
36	2	LOH	R	R	R	R	2.2	3	2	263	1	47	No
37	2	R	R	R	R	R	2.5	10	2	7	0	47	No
38	2	LOH	LOH	R	R	R	1.4	2	2	585	0	65	No
39	2	R	R	R	LOH	LOH	2.1	3	2	11	0	62	No
40	2	LOH	LOH	R	R	LOH	3.5	22	3	33	1	58	No
41	2	R	R	LOH	R	R	2.1	1	2	19	0	53	No
42	2	LOH	R	R	R	LOH	0.9	2	2	5	0	58	No
43	2	LOH	R	LOH	R	LOH	1.8	4	2	14	0	46	No
44	2	LOH	R	LOH	LOH	NI	2.0	7	1	224	0	92	No
45	2	R	NI	LOH	R	R	2.0	50	2	410	1	79	No
46	2	LOH	R	NI	R	R	2.1	9	2	3564	0	87	No
47	2	NI	LOH	NI	R	R	1.5	2	2	24	0	82	No
48	2	R	R	R	R	R	2.7	8	2	8	1	63	No
49	2	LOH	R	NI	R	NI	2.5	3	2	96	1	43	No
50	2	R	R	NI	R	LOH	1.5	2	2	19	0	42	No
51	2	R	NI	NI	LOH	LOH	2.5	4	2	19	0	11	No
52	2	NI	R	R	R	NI	2.5	3	1	4	0	46	No
53	2	NI	LOH	R	R	LOH	2.4	8	2	27	1	46	No
54	2	LOH	R	R	R	R	4.8	2	2	29	0	40	No
55	2	LOH	LOH	LOH	R	LOH	3.0	5	2	2153	1	46	No
56	2	LOH	R	NI	R	LOH	3.0	5	2	22	0	45	No
57	2	LOH	R	LOH	R	R	5.0	1	2	23	1	7	No
58	2	LOH	LOH	NI	LOH	LOH	5.0	5	2	3	1	26	Yes	Lung
59	2	LOH	NI	NI	LOH	LOH	4.0	4	3	1148	0	8	Yes	Lung and diaphragm
60	2	LOH	R	LOH	LOH	LOH	2.1	4	2	53	0	44	Yes	Liver
61	2	LOH	LOH	R	LOH	LOH	3.5	7	3	2363	1	3	Yes	Lung
62	2	LOH	R	R	LOH	LOH	4.9	2	3	779	0	6	Yes	Lymph node
63	2	LOH	LOH	LOH	R	LOH	1.8	96	2	12 727	0	16	Yes	Liver, bone, and lung
64	2	LOH	LOH	LOH	LOH	LOH	3.0	15	2	91	0	18	Yes	Liver, lung, and bone
65	2	LOH	NI	R	LOH	LOH	3.0	40	3	4699	2	6	Yes	Lung and bone
66	2	R	LOH	LOH	LOH	LOH	4.0	380	2	261	1	6	Yes	Lung and bone
67	2	LOH	R	R	R	LOH	4.0	3	3	6736	2	7	Yes	Adrenal gland and bone
68	3	LOH	LOH	LOH	LOH	R	7.0	2	3	529	0	96	No
69	3	LOH	R	LOH	R	R	6.5	4	2	199	0	56	No
70	3	LOH	LOH	NI	LOH	R	3.7	2	2	188	3	104	No
71	3	R	LOH	R	R	LOH	8.0	15	2	5	1	11	No
72	3	LOH	LOH	LOH	R	NI	6.0	2	2	341	3	24	No
73	3	LOH	LOH	NI	LOH	R	6.0	2	2	233	1	41	No
74	3	LOH	LOH	NI	LOH	LOH	5.5	15	3	173	1	3	Yes	Liver, adrenal gland, and brain
75	3	R	LOH	R	R	LOH	9.0	9	2	2093	1	22	Yes	Liver and luns
76	3	LOH	R	LOH	LOH	LOH	8.0	5	3	3209	3	10	Yes	Lymph node
77	3	LOH	R	LOH	R	R	9.1	2	2	20 362	0	30	Yes	Right subphrenic space
78	3	NI	LOH	NI	LOH	R	22.5	23	3	3	1	8	Yes	Diaphragm
79	3	LOH	R	NI	R	R	5.2	4	2	2	2	14	Yes	Liver
80	3	LOH	LOH	R	R	NI	8.5	50	3	212 220	3	9	Yes	Systemic
† HCC invasion into the portal vein was classified as vp0 (none), vp1 (microscopic), vp2 (into the segmental branch), and vp3 (into the lobar vein or the main trunk).
AFP, alpha‐fetoprotein; AJCC, American Joint Committee on Cancer; LOH, loss of heterozygosity; R, retention of heterozigosity; NI, not informative.