Table 3.
Methylation of PCDH10 and human papilloma virus (HPV) typing in cervical swab specimens
| Age ± SE (years) | Methylation (%) | P † | Age ± SE (years) | High‐risk HPV (%) | P † | |
|---|---|---|---|---|---|---|
| Normal | 53.2 ± 1.8 | 0/66 (0) | 53.2 ± 1.8 | 3/65 (4.6) | ||
| LSIL | 46.8 ± 2.1 | 0/27 (0) | 49.2 ± 2.2 | 9/12 (75) | ||
| HSIL exclude CIS | 46.6 ± 5.4 | 0/12 (0) | 52.9 ± 6.7 | 8/8 (100) | ||
| CIS | 49.4 ± 2.4 | 12/43 (27.9) | 52.4 ± 3.6 | 23/23 (100) | ||
| SCC/AdenoCA | 58.9 ± 2.4 | 22/31 (71.0) | 2.31E‐17 | 57.1 ± 2.9 | 21/22 (95.5) | 6.02E‐30 |
†
Fisher's exact test. AdenoCA, adenocarcinoma; CIS, carcinoma in situ; HSIL, high‐grade squamous intra‐epithelial lesion; LSIL, low‐grade squamous intra‐epithelial lesion; SCC, squamous cell carcinoma.