Table 1.
Expression status of HLA class I molecules in bone and soft tissue sarcoma biopsy specimens
| Specimen | n | HLA class I status | ||
|---|---|---|---|---|
| Negative | Low | High | ||
| Bone tumors | ||||
| Osteosarcoma | ||||
| Primary lesion | 25 | 5 | 8 | 12 |
| Lung metastatic lesion | 8 | 6 | 1 | 1 |
| Chondrosarcoma | 5 | 3 | 1 | 1 |
| Bone malignant fibrous histiocytoma | 2 | 1 | 0 | 1 |
| Soft tissue tumors | ||||
| Malignant fibrous histiocytoma | 15 | 2 | 6 | 7 |
| Liposarcoma | 5 | 2 | 2 | 1 |
| Rhabdomyosarcoma | 3 | 1 | 1 | 1 |
| Extraskeletal Ewing sarcoma | 2 | 0 | 1 | 1 |
| Clear cell sarcoma | 2 | 0 | 1 | 1 |
| Synovial sarcoma | 2 | 2 | 0 | 0 |
| Leiomyosarcoma | 2 | 1 | 0 | 1 |
| Alveolar soft‐part sarcoma | 2 | 1 | 0 | 1 |
| Malignant peripheral nerve sheath tumor | 1 | 0 | 1 | 0 |
| Total | 74 | 24 | 22 | 28 |
The distribution of HLA class I‐positive cells was graded as negative (positive cells < 5%), low (5% < positive cells ≤ 50%) or high (positive cells > 50%).