Table 1.
Polymorphisms reported in association with Helicobacter pylori infection and odds ratio (OR) or seropositive percentage (HP%)
| Polymorphism | Subjects | OR or HP% |
|---|---|---|
| CD14 C‐159T | 1374 Japanese( 42 ) | TT, TC:0.94, CC:1.16 |
| CXCR2 C785T | 241 Japanese( 42 ) | CC(65%), CT(63%), TT(56%) |
| FUT2 Se/se | 241 Japanese( 43 ) | SeSe, Sese:0.79, sese:0.35* |
| 679 Japanese( 44 ) | SeSe, Sese:1.51*, sese:1.50 | |
| 465 Japanese( 44 ) | SeSe, Sese:1.57, sese:1.29 | |
| FUT3 Le/le | 241 Japanese( 43 ) | LeLe, Lele:1.95*, lele:2.80 |
| 679 Japanese( 44 ) | LeLe, Lele:0.98, lele:1.31 | |
| 465 Japanese( 44 ) | LeLe, Lele:1.06, lele:1.40 | |
| IL‐1 A C‐889T | 241 Japanese( 45 ) | CC(62%), CT/TT(68%) |
| IL‐1B C‐31T | 241 Japanese( 45 ) | CC, CT:2.32*, TT:2.46* |
| 55 smokers | CC, CT:6.18*, TT:22.9* | |
| 465 Japanese( 46 ) | CC, CT:0.97, TT:1.73* | |
| 80 ever smokers | CC, CT:1.68, TT:5.29* | |
| 547 Japanese( 47 ) | CC, CT:1.32, TT:1.35 | |
| 127 smokers | CC, CT:1.12, TT:1.01 | |
| 963 Japanese Brazilians( 48 ) | CC, CT:1.30, TT:1.45* | |
| 124 smokers | CC, CT:2.45, TT:3.49* | |
| IL‐1B C‐511T | 499 Japanese( 49 ) | CC(53%), CT(54%), TT(52%) |
| 474 Koreans( 50 ) | CC(88%), CT(86%), TT(86%) | |
| IL‐1RI C‐116T | 241 Japanese( 42 ) | CC(65%), CT(58%), TT(72%) |
| IL‐1RN VNTR | 241 Japanese( 45 ) | 4rpt/4rpt(62%), others(67%) |
| 474 Koreans( 50 ) | non‐2rpt(87%), 2rpt(80%) | |
| IL‐2 T‐330G | 454 Japanese( 51 ) | GG, TG:1.10, TT:1.15 |
| IL‐4 C‐33T | 454 Japanese( 51 ) | CC, CT:1.43, TT:1.25 |
| IL‐8 T‐251A | 454 Japanese( 52 ) | TT, TA:0.86, AA:0.70 |
| IL‐10 T‐819C | 454 Japanese( 52 ) | TT, TC:0.67, CC:0.82 |
| IL‐8 & IL‐10 | 454 Japanese( 52 ) | TT & TT, others:0.62* |
| 65 smokers | TT & TT, others:0.13* | |
| 241 Japanese( 42 ) | TT & TT, others:1.04 | |
| 55 smokers | TT & TT, others:0.45 | |
| 679 Japanese( 42 ) | TT & TT, others:1.49* | |
| 158 smokers | TT & TT, others:0.89 | |
| IL‐13 C‐1111T | 454 Japanese( 51 ) | CC, CT:0.73, TT:1.09 |
| MPO G‐463A | 241 Japanese( 53 ) | GG, GA/AA:0.69 |
| 55 smokers | GG, GA/AA:0.21* | |
| 454 Japanese( 54 ) | GG, GA/AA:0.84 | |
| 64 smokers | GG, GA/AA:0.83 | |
| NF‐KB2–10G I/D | 1374 Japanese( 42 ) | II, ID:1.03, DD:1.15 |
| NQO1 C609T | 241 Japanese( 55 ) | TT, TC:1.13, CC:2.42* |
| 454 Japanese( 55 ) | TT, TC:1.57, CC:1.70 | |
| PPAP Pro12Ala(C/G) | 104 Chinese( 56 ) | CC(62%), CG/GG(33%) |
| PTPN11 G/A at intron 3 | 454 Japanese( 57 ) | GG(58%), GA(49%), AA(47%) |
| TCRBV6S1 A/B | 383 Germans( 58 ) | Significant association* |
| TNF‐A T‐1031C | 1374 Japanese( 59 ) | TT, TC:0.62, CC:0.43* |
| 963 Japanese Brazilians( 60 ) | CC, TC:0.96, TT:1.18 | |
| TNF‐A C‐857T | 1374 Japanese( 59 ) | CC, CT:1.06, TT:1.69 |
| 963 Japanese Brazilians( 60 ) | CC, CT:1.17, TT:1.21 | |
| TNF‐A−1031 & −857 | 1374 Japanese( 59 ) | CC & CC, TT & CC:2.37*, TC & CT:2.84*, TT & TT:3.63* |
| 963 Japanese Brazilians( 60 ) | CC & CC, TT & CC:1.08, TC & CT:1.03, TT & TT:1.27 | |
| 253 ever smokers CC & CC, TT & CC:2.01, TC & CT:1.76, TT & TT:2.30 | ||
| TNF‐A G‐308A | 393 Germans( 61 ) | GG(52%), GA(56%), AA(56%) |
| 792 Italians( 62 ) | GG(54%), GA(61%*), AA(–) | |
| 474 Koreans( 50 ) | GG(86%), GA/AA(89%) | |
| TNF‐B A252G | 1374 Japanese( 59 ) | AA, AG:1.05, GG:1.05 |
*
Statistically significant (P < 0.05).