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Human Scribble negatively regulates cell‐cycle progression from G1 to S phase. The cell‐cycle profiles of NIH3T3 cells transfected with (A) pEGFP vector or (B) pEGFP‐hScrib were analyzed by flow cytometry. The result is representative of three independent experiments. The percentage of cells in S phase was lower in the cells transfected with pEGFP‐hScrib than the cells transfected with pEGFP vector.
