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Effects of ONO‐8711 on histological types of AOM‐induced colon carcinomas
| Treatment | Effective no. of animals | Total no. of carcinomas (%) | No. of carcinomas diagnosed | |||
|---|---|---|---|---|---|---|
| Well‐ differentiated (%) | Moderately‐ differentiated (%) | Signet‐ring cell (%) | Mucinous (%) | |||
| AOM alone | 35 | 116 (100) | 108 (93) | 3 (3) | 1 (1) | 4 (3) |
| AOM + ONO‐8711, 400 p.p.m. | 35 | 82 (100) | 77 (94) | 2 (2) | 3 (4) | 0 (0) |
| AOM + ONO‐8711, 800 p.p.m. | 33 | 68 (100) | 65 (96) | 0 (0) | 2 (3) | 1 (1) |
