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Table 2.

TLR2 polymorphism and risk of gastric cancer (compared with healthy control subjects)

Variable TLR2 genotype (%) OR (95% CI) ins/ins vs ins/del P‐value OR (95% CI) ins/ins vs del carriers P‐value OR (95% CI) del/del vs others P‐value
ins/ins ins/del del/del
Healthy control subjects (n = 146)  73 (50.0)  65 (44.5)  8 (5.5) Reference Reference Reference
NCGC (n = 289) 126 (43.6) 112 (38.8) 51 (17.6) 1.00 (0.66–1.52) 1 1.29 (0.87–1.93) 0.22 3.70 (1.70–8.02) 0.0009

Age, sex‐adjusted OR = 6.06 (95% CI = 1.86–19.72), P = 0.003. Statistical significance was assessed using the two‐sided Fisher's exact test. CI, confidence interval; del carriers, ins/del + del/del; NCGC, non‐cardiac gastric cancer; OR, odds ratio.