Table 3.
Cumulative smoking dose and clinical outcomes
| Smoking dose (pack‐years [PY]) | Number | Response rate (%) | P‐values* | MST (months) | P‐values* | MPFS (months) | P‐values* |
|---|---|---|---|---|---|---|---|
| 0 (Never‐smokers) | 178 | 94 (52.8%) | 18.3 | 6.3 | |||
| 0 < PY < 13 | 33 | 15 (45.5%) | 0.78 | 18.7 | 0.71 | 5.1 | 0.61 |
| 13 < PY < 40 | 92 | 26 (28.3%) | 0.019 | 9.6 | 0.0024 | 2.6 | 0.0015 |
| 40 < PY | 105 | 21 (20.0%) | 0.0004 | 9.5 | 0.0015 | 2.2 | < 0.0001 |
*
The difference was examined between pack‐year categories and never‐smokers.
MPFS, median progression‐free survival time; MST, median survival time.