Table 1.
Characteristic | 200 mg bid (n = 13) | 400 mg bid (n = 14) | Total (n = 27) |
---|---|---|---|
Sex (n) | |||
Male | 12 | 13 | 25 |
Female | 1 | 1 | 2 |
Median age (years) | 69 (range 48–77) | 70 (range 63–79) | 70 (range 48–79) |
Eastern Cooperative Oncology Group performance status | |||
0 | 13 | 14 | 27 |
Child–Pugh classification | |||
A | 7 | 6 | 13 |
B | 6 | 8 | 14 |
Viral markers | |||
HB antigen+, HCV antibody− | 3 | 1 | 4 |
HB antigen−, HCV antibody+ | 9 | 11 | 20 |
HB antigen−, HCV antibody− | 1 | 2 | 3 |
Previous treatment | |||
– | 1 | 3 | 4 |
+ | 12 | 11 | 23 |
Tumor stage | |||
II | 1 | 2 | 3 |
III | 7 | 8 | 15 |
IVa | 1 | 1 | 2 |
IVb | 4 | 3 | 7 |
Portal vein tumor thrombus | |||
– | 12 | 13 | 25 |
+ | 1 | 1 | 2 |
Metastasis | |||
– | 9 | 11 | 20 |
+ | 4 | 3 | 7 |
Lung | 3 | 1 | 4 |
Lung + lymph node | 1 | 1 | 2 |
Lymph node | 0 | 1 | 1 |
HB, hepatitis B; HCV, hepatitis C virus.