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Table 1.

Patient characteristics

Characteristic 200 mg bid (n = 13) 400 mg bid (n = 14) Total (n = 27)
Sex (n)
 Male 12 13 25
 Female  1  1  2
Median age (years) 69 (range 48–77) 70 (range 63–79) 70 (range 48–79)
Eastern Cooperative Oncology Group  performance status
 0 13 14 27
Child–Pugh classification
 A  7  6 13
 B  6  8 14
Viral markers
 HB antigen+, HCV antibody  3  1  4
 HB antigen, HCV antibody+  9 11 20
 HB antigen, HCV antibody  1  2  3
Previous treatment
 –  1  3  4
 + 12 11 23
Tumor stage
 II  1  2  3
 III  7  8 15
 IVa  1  1  2
 IVb  4  3  7
Portal vein tumor thrombus
 – 12 13 25
 +  1  1  2
Metastasis
 –  9 11 20
 +  4  3  7
 Lung  3  1  4
 Lung + lymph node  1  1  2
 Lymph node  0  1  1

HB, hepatitis B; HCV, hepatitis C virus.