. 2006 Dec 11;98(2):246–252. doi: 10.1111/j.1349-7006.2006.00377.x

Table 3.

Mutations of the epidermal growth factor receptor gene. The change in amino acid sequence and the change in the nucleotide sequence are shown for each mutation. A letter before each sequence corresponds to that shown in Fig. 2C

		No.	No.
Exon 19 deletions		29
c	E746‐A750del		13
c	2235–2249delGGAATTAAGAGAAGC
c	E746‐A750del		7
c	2236–2250delGAATTAAGAGAAGCA
h	L747‐S752del E746V		1
h	2238–2255delATTAAGAGAAGCAACATC, 2237 A > T
j	L747‐E749del A750P		2
j	2239–2247delTTAAGAGAA, 2248G > C
k	L747‐A750del T751S		1
k	2240–2251delTAAGAGAAGCAA
r	L747‐S752del P753S		3
	2240–2257delTAAGAGAAGCAACATCTC
	L747‐T751del		1 ^†
	2238–2252delATTAAGAGAAGCAAC
	L747‐T753del ins A		1 ^‡
	2239–2258delTTAAGAGAAGCAACA, ins GCT
Exon 21 point mutations		16
y	L858R
y	2573T > G		15
z	L861Q		1
z	2582T > A

^{^†}

Mutations determined by the direct sequencing of the peptide nucleic acid‐locked nucleic acid polymerase chain reaction clamp product.

^{^‡}

Chromatogram of the direct sequence is shown in Fig. 3B