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Regulation of caspase‐8 activity by wortmannin, LY294002 and TRAIL. The bladder cancer cells were treated with wortmannin (1 µM) or LY‐294002 (25 µM) in the presence or absence of TRAIL (100 ng/mL) for 12 h, and caspase‐8 activity was measured at 405 nm using a Spectra Maxi Germini fluorescence plate reader. Data are expressed as the mean ± SD.
