Expression of vascular endothelial growth factor receptor 2 (VEGFR‐2), matrix metalloproteinase 1 (MMP‐1), and MMP‐9 in SCC‐S2 ‐depleted H1299 and A549 cells. (a) Real‐time PCR and (b) western blot analysis showed the expression changes after silencing SCC‐S2 in H1299 and A549 cells. The expression of VEGFR‐2, MMP‐1, and MMP‐9 was explored. Columns, mean; bars, SD.