Skip to main content
. 2009 May 12;100(9):1648–1654. doi: 10.1111/j.1349-7006.2009.01214.x

Figure 5.

Figure 5

Influence of Sprouty4 deficiency on vascular endothelial growth factor (VEGF)‐A signaling. (a,b) Wild‐type (WT) and Sprouty4 knockout (KO) mouse embryonic fibroblasts (MEFs) (a) or WT and Sprouty2/Sprouty4 double KO (DKO) MEFs (b), which stably expressed VEGFR‐2, were stimulated with 50 ng/mL VEGF‐A. The relative ratio of the band intensity of phosphorylated ERK1/2 versus that of total ERK2 is shown in the right (a). (c) Inferior venae cavae of WT and Sprouty4 KO were stimulated with 100 ng/mL VEGF‐A. (a–c) Cell extracts were immunoblotted with the indicated antibodies.