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Figure 3.

Figure 3

The mean (SD) tumor weights (g) in the FU‐MMT‐1 xenografts resected after treatment. The mean tumor weight after treatment of either ultrasound (US) alone (10.98 ± 2.27 g, range: 4.8–17.2 g) or TNP‐470 alone (8.94 ± 3.07 g, range: 3.1–21.2 g) was smaller than that of the control (25.04 ± 3.85 g, range: 7.6–30.8 g; Mann–Whitney‐U‐test, vs US alone: P = 0.0042; vs TNP‐470 alone; P = 0.025). The enhanced effect of the weight reduction in xenografts was shown by the combined treatment (0.75 ± 0.52 g, range; 0.0–4.8 g), in comparison to either US alone (P = 0.027) or TNP‐470 alone (P = 0.050). The mean tumor weight of the xenografts measured after the combined treatment was significantly lower than that of the control (P = 0.0007).