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. 2005 Sep 1;96(10):695–705. doi: 10.1111/j.1349-7006.2005.00093.x

Figure 4.

Figure 4

Vaccination with HSP105 DNA induced infiltration of both CD4+ T cells and CD8+ T cells into C26 tumors, but not into normal tissues. (a) Subcutaneous C26 tumors removed from two HSP105 DNA‐immunized mice, a saline‐inoculated mouse, and a pCAGGS‐immunized mouse that did not reject the tumor challenges were analyzed using immunohistochemical staining with anti‐CD4 mAb and anti‐CD8 mAb. (b) Normal tissues of mice vaccinated with HSP105 DNA were histologically and immunohistochemically examined. Objective magnification was 200×. The spleen was used as a positive control for staining of both CD4 and CD8.