Figure 9.

Growth inhibition of Colo320 and Colo320TP1 cells in the hollow fibers implanted s.c. in mice. The mice were treated with the formulation TAS‐102 or with thymidine analog trifluorothymidine (TFT) a; one at the same dose. Four to five fibers per cell line, all implanted in different mice, were assayed. Values are Means ± standard error. In vitro control, fibers were incubated in DMEM culture medium. Compared to in vivo fiber control, *P < 0.05; to Colo320, **P < 0.05. Data were adapted from Temmink et al. (2007; with permission).^{( 61 )}