Figure 6.

A suggested scheme for the influence of cyclin A1 siRNA on specific apoptotic pathways in lung cancer. siRNA for cyclin A1 in lung cancer leads to apoptosis through the upregulation of a member of the TNF receptor family in the extrinsic pathway, downregulation of the intrinsic pathway, decreased survivin in the final common pathway and v‐myb avian myeloblastosis viral oncogene homolog‐like 2 in the oncogene group, protein phosphatase 2 in the modulator category. ^# Log₂R/G ratio, P < 0.05.