Figure 1.

Chromosomal copy number changes revealed by array‐based comparative genomic hybridization. Representative array‐based comparative genomic hybridization profile of a pancreatic adenocarcinoma. Copy number losses (ratio < 0.75) and gains (ratio > 1.25) were detected in both large fractions of the chromosome arms and small chromosomal regions. Amplifications (ratio > 2.00, arrowheads) and homozygous deletions (ratio < 0.25, arrow) were also identified in this tumor. The average signal ratios (test:reference) of two normalized signals from duplicated spots are given from chromosome 1p telomere (left) to Xq telomere (right). The vertical dotted and continuous lines indicate the position of the centromere and telomere of each chromosome, respectively.