Table 4.
Loci altered frequently in pancreatic adenocarcinoma cases with short‐survival (<1 year) compared with long‐survival periods
| Chromosomal locus | Contained cancer‐ related gene | Sub‐chromosomal loss detected | P value† | |||
|---|---|---|---|---|---|---|
| Venous invasion‐positive cases | Venous invasion‐negative cases | |||||
| n | % | n | % | |||
| 1p36.33 | TP73 | 9 | 69 | 4 | 21 | 0.006 |
| 8q24.3 | GLI4 | 5 | 38 | 1 | 5 | 0.018 |
| Xq12 | AR | 5 | 38 | 1 | 5 | 0.018 |
| 11q13 | STIP1, FOLR1 | 8 | 62 | 5 | 26 | 0.046 |
| 20q11.2 | LUNX, TOP1 | 5 | 38 | 0 | 0 | 0.003 |
| 18p11.3 | TGIF | 6 | 46 | 1 | 5 | 0.006 |
| 4q13‐q21 | AREG | 4 | 31 | 0 | 0 | 0.010 |
| 6q21 | CCNC | 4 | 31 | 0 | 0 | 0.010 |
| 10q21.1 | PCDH15 | 10 | 77 | 6 | 32 | 0.012 |
| 1p32 | RLF | 5 | 38 | 1 | 5 | 0.018 |
| 2q36 | Cul3 | 8 | 62 | 4 | 21 | 0.020 |
| 17q23 | PPM1D | 8 | 62 | 4 | 21 | 0.020 |
| 4q21 | GRO1 | 6 | 46 | 2 | 11 | 0.022 |
| 1p36.2 | KIAA0591(KIF1B) | 7 | 54 | 3 | 16 | 0.023 |
| 4q21 | GRO2 | 7 | 54 | 3 | 16 | 0.023 |
| 13q32 | GPC5 | 7 | 54 | 3 | 16 | 0.023 |
| 8q22‐q23 | EIF3S6 | 9 | 69 | 6 | 32 | 0.036 |
†
χ2 test.