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. 2008 Nov 27;100(1):117–125. doi: 10.1111/j.1349-7006.2008.01017.x

Figure 3.

Figure 3

Constitutively active RAF (caRAF) promotes cell cycle progression, and MEK inhibitor causes cell cycle to delay in phases G1 to S. The number in the frame represents the mean ± standard deviation of three independent experiments, Fisher's exact test. (a) Flow cytometry analysis of the distribution of cell cycle phases in GES‐1 and AGS, expressing caRAF or vector. (b) The percentage of cells in each cell cycle phase was quantitated using CellQuest software. (c) Flow cytometry analysis cell cycle distribution of caRAF‐GES‐1 or caRAF‐AGS cells treated with PD98059 or dimethylsulfoxide (DMSO) for 24 h. (d) The percentage of each cell cycle phase in caRAF‐expressing cells with PD98059 or DMSO.