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Reversal of BCRP‐mediated drug resistances
| RI50 values (μmol/L) for K562/BCRP | |
|---|---|
| Sunitinib | |
| MXR | 0.10 ± 0.003 |
| SN‐38 | 0.064 ± 0.004 |
Results are means ± SD of triplicate experiments. BCRP, breast cancer resistance protein; MXR, mitoxantrone; RI50, 50% reversal index; SN‐38, 7‐ethyl‐10‐hydroxycamptotecin.
