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. 2009 Sep 29;101(2):440–447. doi: 10.1111/j.1349-7006.2009.01375.x

Table 1.

 Characteristics of colorectal cancer cell lines used in this analysis

EGFR p53 Braf k‐Ras PTEN IC50 erlotinib (μM) IC50 TFT (μM)
WiDR w.t. mut mut w.t w.t. 8.2 ± 0.8 3.2 ± 0.3
Lovo92 w.t. w.t. w.t. mut w.t. 4.4 ± 1.3 0.9 ± 0.1
Colo320 w.t. w.t.† w.t. mut w.t. 3.2 ± 0.3 0.6 ± 0.1
Caco2 w.t. w.t. w.t. w.t. w.t. 0.3 ± 0.1 25 ± 2.0

†Colo320 is w.t. p53, but lacks p21 (see Fig. 1) and therefore behaves as a mutant. EGFR, epidermal growth factor receptor; mut, mutant; TFT, trifluorothymidine; w.t., wild type.