Figure 3.

Retinoic acid receptor (RAR) β localization in eutopic endometrium, endometrial hyperplasia, and endometrial carcinoma. (a,b) In ectopic endometrium, RARβ immunoreactivities were detected in the nuclei of epithelial cells throughout all menstrual phases. (c) In endometrial hyperplasia, RARβ immunoreactivity was detected in the nuclei of 60–75% of stromal cells. In endometrial carcinoma, no RARβ immunoreactivity was detected in the stromal cells in any of the cases examined. (d) RARβ immunoreactivities were detected in the nuclei of 18–37% of carcinoma cells. Immunohistochemistry for the RAR was carried out using serial sections of eutopic endometrium, endometrial hyperplasia, and endometrial carcinoma. (Original magnification, ×200.)