Figure 6.

 Ectopic expression of Clast1/LR8 inhibits H‐RasV12‐induced tumor formation in nude mice. (a) One million cells of each type indicated were injected s.c. into the right flanks of 5‐week‐old nude mice and tumor volumes were assessed every 2–5 days for 20 days. Images show representative mice from each injection group. (b) Tumor growth rates in mice injected with H‐RasV12 NIH3T3 cells transfected with either empty vector or Clast1/LR8 expression vector. Values represent the mean ± SD of three separate experiments. **P < 0.01.