Table 1.

Number of genes significantly correlated with antitumor activity to seven anticancer drugs

	Number of genes
	Positive correlation	Negative correlation	Total
UFT	72	59	131
S‐1	84	31	115
Capecitabine	128	64	192
5′‐DFUR	110	85	195
CDDP	25	88	113
CPT‐11	99	90	189
Paclitaxel	30	35	65

Correlation analysis between 4144 probe sets and antitumor activity for seven anticancer drugs across 30 xenografts were carried out to screen the genes that correlated with sensitivity to the drug sensitivity. Genes were selected that represented the significant correlation that satisfied the following criteria: P < 0.05, and the absolute value of the slope of the regression line was >1.5 where the difference of the drug sensitivity between the most and the least xenografts was fixed as 1. CDDP, cisplatin; CPT‐11, irinotecan hydrochloride; 5′‐DFUR, 5′‐deoxy‐5‐fluorouridine; S‐1, 1 M tegafur−0.4 M 5‐chloro‐2,4‐dihydroxypyridine−1 M potassium oxonate; UFT, 1 M tegafur−4 M uracil.