Table 2.

UGT1A1 genetic profiles and plasma concentration–time curve (AUC) ratios

UGT1A1*6	UGT1A1*28	n †	AUCSN‐38/AUCSN‐38G
–/–	–/–	24	0.43 (0.08–1.39) ‡
+/–	–/–	15	0.61 (0.26–1.42) ‡
+/+	–/–	2	1.40, 1.10
–/–	+/–	2	0.48, 0.44
+/–	–/+	2	1.04, 2.16

^† Total n = 45. One patient was excluded because of an incomplete set of blood samples;

^{‡ ‡} median (range).