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. 2011 Apr 27;102(6):1137–1143. doi: 10.1111/j.1349-7006.2011.01936.x

Figure 2.

Figure 2

 Knockdown of Insig2 expression in pancreatic cancer cell lines by Insig2‐targeting siRNAs and the effects on cell proliferation and invasion. (a) Insig2 expression is significantly suppressed by the Insig2‐targeting siRNAs in SUIT‐2, Capan‐2, and CFPAC‐1 cells. (b) Decreased proliferation is observed in SUIT‐2 cells transfected with the Insig2‐targeting siRNAs compared with the control cells at 120 h after transfection (*P < 0.01, Student’s t‐test). (c) Decreased invasion is observed in SUIT‐2, Capan‐2, and CFPAC‐1 cells transfected seen with the Insig2‐targeting siRNAs compared with the control cells at 48 h after seeding (*P < 0.01, Student’s t‐test). The data are the means ± SD of triplicate measurements.