Table 2.

Relationship between cyclin E and manganese superoxide dismutase (MnSOD) expression and main tumor characteristics in a series of 134 early breast cancer patients receiving adjuvant epirubicin‐based regimens

Characteristic		Cyclin E expression			MnSOD expression
	Total	Low	High	P‐value	Negative	Positive	P‐value
Age (years)
≤50	65	40	25		35	30
>50	69	48	21	0.4	43	26	0.4
Node status
Negative	64	47	17		34	30
Positive	70	41	29	0.1	44	26	0.3
ER expression
Negative	60	39	21		34	26
Positive	68	43	25	0.8	44	24	0.4
PgR expression
Negative	74	48	26		46	28
Positive	52	35	17	0.8	26	26	0.2
Grading † , ‡
G2	45	29	16		22	23
G3	83	56	27	0.8	51	32	0.2
Size §
pT1	70	52	18		46	24
pT2–3	64	36	28	0.03	32	32	0.08

^† Not available in some patients.

^‡ According to Elston and Ellis classification (see text for complete reference^{( 24 )}).

^§ According to UICC – TNM classification of malignant tumors, sixth edition 2002.^{( 23 )}