Table 3.

Relationship between disease relapse, patient survival and various clinical and molecular parameters in a series of 134 early breast cancer patients receiving adjuvant epirubicin‐based regimens

Paramater	Total	Disease relapse			Patient death
		No	Yes	P‐value	No	Yes	P‐value
Age (years)
≤50	65	27	38		48	17
>50	69	37	32	0.77	47	22	0.66
Node status
Negative	64	37	27		47	17
Positive	70	27	43	0.037	48	22	0.3
Cyclin E expression
Low	88	46	42		69	19
High	46	18	28	0.2	26	20	0.01
MnSOD expression
Negative	78	35	43		26	52
Positive	56	29	27	0.48	43	13	0.24
ER expression
Negative	60	30	30		41	19
Positive	68	32	36	0.8	49	19	0.74
PgR expression
Negative	74	32	42		50	24
Positive	52	30	24	0.33	38	14	0.45
Grading † , ‡
G2	45	21	24		29	16
G3	83	44	29	0.71	56	27	0.88
Size §
pT1	70	42	28		54	16
pT2–3	64	22	42	0.035	41	23	0.17

^† Not available in some patients.

^‡ According to Elston and Ellis classification (see text for complete reference^{( 24 )}).

^§ According to UICC – TNM classification of malignant tumors, sixth edition 2002.^{( 23 )} MnSOD, manganese superoxide dismutase.