Table 2.

Blood chemistry of patients

Liver function	Grade
	0	1	2	3
Albumin
Concentration (g/dL)	≥4.0	3.0–3.9	2.0–2.9	≤1.9
No. patients	63	126	10	1
Total bilirubin
Concentration (mg/dL)	≤1.2	1.3–1.5	1.6–3.6	3.7–12
No. patients	195	3	1	1
Aspartate aminotransferase
Concentration (IU/L)	≤33	34–82	83–165	166–660
No. patients	157	27	10	6
Alanine aminotransferase
Concentration (IU/L)	≤27	28–67	68–135	136–540
No. patients	145	43	6	6
Alkaline phosphatase
Concentration (IU/L)	≤359	360–897	898–1795	1796–7140
No. patients	160	26	11	3
α1‐Acid glycoprotein
Concentration (mg/dL)	≤93 †	94–232 ‡	233–465 §
No. patients	90	107	3

^† ≤Upper limit of normal range (ULN);

^‡ >ULN and ≤2.5 × ULN;

^§ >2.5 × ULN and ≤5 × ULN.