The effect of a dipeptidyl peptidase IV (DPPIV) inhibitor (diprotin A, DPA) on chemosensitivity to paclitaxel in either DPPIV‐transfected SKDP or natively DPPIV‐overexpressing NOS‐2 cells. (A) The DPPIV activity of SKDP cells with or without DPA (100 μm). (a) P < 0.001, SKpc versus SKDP cells; (b) P < 0.001, SKDP versus SKDP/DPA cells. (B) The surface expressions of DPPIV in the presence or absence of DPA (100 μm, 72 h). DPA‐treatment did not alter the surface expression levels of DPPIV in SKDP cells. White peak, SKDP/DPA cells; gray peak, SKDP cells. (C) Inhibition of DPPIV activity by the addition of DPA (100 μm) in SKpc and SKDP cells. (D) Inhibition of DPPIV activity by the addition of DPA (100 μm) in NOS‐2 cells.