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. 2007 Apr 18;98(7):1064–1069. doi: 10.1111/j.1349-7006.2007.00487.x

Figure 4.

Figure 4

Erk1/2 was involved in regulation of MDR1, MMP2,9 by CD147. Activation state of three pathways of MAP kinase (MAPK) (a) in tumor cells were first examined by immunoblot analysis. To determine the effects of U0126, MT3 cells were treated with various concentrations of u‐0126 or vehicle for 24 h in serum‐free media. At the end of incubation, the expression of MDR1, MMP2, and MMP9 were analyzed by Western blot. (b) Bar graphs quantified and compared the immunoblots signal intensity. **P < 0.05 vs control cells.